Application
ATXN1L Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ATXN1L antibody detected the ATXN1L protein (arrow).| Product Name | ATXN1L Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BOAT, BOAT1 |
|---|---|
| Alternative Names | ATXN1L BOAT BOAT1 Ataxin-1-like Brother of ataxin-1 |
| Molecular Weight(MW) | 73306 Da |
| Function | Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Can suppress ATXN1 cytotoxicity in spinocerebellar ataxia type 1 (SCA1) (By similarity) |
| Tissue Specificity | Expressed in cerebellum and cerebral cortex. |
| Cellular Localization | Nucleus. Cell projection, dendrite. Note=Forms nuclear foci. Colocalizes with NCOR2 and HDAC3 Distributed beyond the nucleus into the cell body and dendrites in Purkinje cells and in inferior olive cells |
| Entrez Gene | 342371 |
|---|---|
| Nucleotide Accession | NP_001131147.1 |
Application
ATXN1L Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the ATXN1L antibody detected the ATXN1L protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
