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AXIN2 Antibody (C-term)

Catalog Number:OM227303
OM227303
Discount Price
OM227303-100ul
1~2 Week
100ul
OM227303-50ul
50ul
OM227303-20ul
20ul
1~2 Week
Product Profile
Product Name AXIN2 Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names AXIN2
Axin-2
Axin-like protein
Axis inhibition protein 2
Conductin
Molecular Weight(MW) 93558 Da
Function Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta- catenin and APC by GSK3B (By similarity)
Tissue Specificity Expressed in brain and lymphoblast.
Cellular Localization Cytoplasm.
Database Links
Entrez Gene 8313
Nucleotide Accession NP_004646.3
Application

Application

AXIN2 Antibody (C-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the AXIN2 antibody detected the AXIN2 protein (arrow).

Application

AXIN2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the AXIN2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

AXIN2 Antibody (C-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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