Application
B3GNT5 Antibody (Center) western blot analysis in 293,MDA-MB435,HL-60 cell line lysates (35ug/lane).This demonstrates the B3GNT5 antibody detected the B3GNT5 protein (arrow).Application
Western blot analysis of B3GNT5 Antibody (Center) in mouse liver tissue lysates (35ug/lane). B3GNT5 (arrow) was detected using the purified Pab.| Product Name | B3GNT5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | B3GNT5 Lactosylceramide 1 3-N-acetyl-beta-D-glucosaminyltransferase Lactotriaosylceramide synthase UDP-GlcNAc:beta-Gal beta-1 3-N-acetylglucosaminyltransferase 5 |
|---|---|
| Molecular Weight(MW) | 44053 Da |
| Function | Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc(4)Cer; paragloboside), resulting in the synthesis of Lc(3)Cer and neolactopentaosylceramide (nLc(5)Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development |
| Tissue Specificity | Widely expressed. Highly expressed in lung, colon, placenta, testis, pituitary gland and cerebellum. Weakly expressed in brain, liver, spleen, lymph node and thymus |
| Cellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein (By similarity) |
| Entrez Gene | 84002 |
|---|
Application
B3GNT5 Antibody (Center) western blot analysis in 293,MDA-MB435,HL-60 cell line lysates (35ug/lane).This demonstrates the B3GNT5 antibody detected the B3GNT5 protein (arrow).
Application
Western blot analysis of B3GNT5 Antibody (Center) in mouse liver tissue lysates (35ug/lane). B3GNT5 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
