Application
BCAR1 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the BCAR1 antibody detected the BCAR1 protein (arrow).Application
BCAR1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BCAR1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | BCAR1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CAS, CASS1, CRKAS |
|---|---|
| Alternative Names | BCAR1 CAS CASS1 CRKAS Breast cancer anti-estrogen resistance protein 1 CRK-associated substrate Cas scaffolding protein family member 1 p130cas |
| Molecular Weight(MW) | 93372 Da |
| Function | Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells |
| Tissue Specificity | Widely expressed with an abundant expression in the testis. Low level of expression seen in the liver, thymus, and peripheral blood leukocytes. The protein has been detected in a B-cell line |
| Cellular Localization | Cell junction, focal adhesion. Cytoplasm. Note=Unphosphorylated form localizes in the cytoplasm and can move to the membrane upon tyrosine phosphorylation (By similarity) |
| Entrez Gene | 9564 |
|---|---|
| Nucleotide Accession | NP_001164191.1 NP_001164187.1 NP_001164186.1 NP_001164192.1 NP_001164185.1 NP_001164188 |
Application
BCAR1 Antibody (C-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the BCAR1 antibody detected the BCAR1 protein (arrow).
Application
BCAR1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BCAR1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
