Application
Western blot analysis of anti-BRCA2 and CDKN1A Interacting Protein Pab in A375 cell line lysate. BRCA2 and CDKN1A Interacting Protein(arrow) was detected using the purified Pab.| Product Name | BCCIP Antibody (Center)) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BCCIP; TOK1; BRCA2 and CDKN1A-interacting protein; P21- and CDK-associated protein 1; Protein TOK-1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | TOK1 |
|---|---|
| Alternative Names | BCCIP TOK1 BRCA2 and CDKN1A-interacting protein P21- and CDK-associated protein 1 Protein TOK-1 |
| Molecular Weight(MW) | 35979 Da |
| Function | May promote cell cycle arrest by enhancing the inhibition of CDK2 activity by CDKN1A. May be required for repair of DNA damage by homologous recombination in conjunction with BRCA2. May not be involved in non-homologous end joining (NHEJ) |
| Tissue Specificity | Expressed at high levels in testis and skeletal muscle and at lower levels in brain, heart, kidney, liver, lung, ovary, pancreas, placenta, and spleen |
| Cellular Localization | Nucleus. Note=Colocalizes with BRCA2 in discrete nuclear foci |
Application
Western blot analysis of anti-BRCA2 and CDKN1A Interacting Protein Pab in A375 cell line lysate. BRCA2 and CDKN1A Interacting Protein(arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
