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BCDO2 Antibody (N-term)

Catalog Number:OM227494
OM227494
Discount Price
OM227494-100ul
1~2 Week
100ul
OM227494-50ul
50ul
OM227494-20ul
20ul
1~2 Week
Product Profile
Product Name BCDO2 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias BCO2; BCDO2; Beta, beta-carotene 9', 10'-oxygenase; B-diox-II; Beta-carotene dioxygenase 2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms BCDO2
Alternative Names BCO2
BCDO2
Beta
beta-carotene 9'
10'-oxygenase
B-diox-II
Beta-carotene dioxygenase 2
Molecular Weight(MW) 65674 Da
Function Asymmetrically cleaves beta-carotene at the 9',10' double bond resulting in the formation of beta-apo-10'-carotenal and beta-ionone. Besides beta-carotene, lycopene is also oxidatively cleaved. The apocarotenals formed by this enzyme may be the precursors for the biosynthesis of retinoic acid or exert unknown physiological effects
Tissue Specificity Highly expressed in retinal pigment epithelium. Also expressed in stomach, small intestine, liver, testis, kidney, adrenal gland, pancreas, heart, skeletal muscle and prostate (at protein level)
Cellular Localization Mitochondrion.
Database Links
Entrez Gene 83875
Nucleotide Accession NP_001032367.1 NP_114144.3
Application

Application

BCDO2 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the BCDO2 antibody detected the BCDO2 protein (arrow).
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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