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Bcl-6 Antibody (C-term)

Catalog Number:OM227510
OM227510
Discount Price
OM227510-100ul
1~2 Week
100ul
OM227510-50ul
50ul
OM227510-20ul
20ul
1~2 Week
Product Profile
Product Name Bcl-6 Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms BCL5, LAZ3, ZBTB27, ZNF51
Alternative Names BCL6
BCL5
LAZ3
ZBTB27
ZNF51
B-cell lymphoma 6 protein
B-cell lymphoma 5 protein
Protein LAZ-3
Zinc finger and BTB domain-containing protein 27
Zinc finger protein 51
Molecular Weight(MW) 78846 Da
Function Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis
Tissue Specificity Expressed in germinal center T and B-cells and in primary immature dendritic cells
Cellular Localization Nucleus (By similarity).
Database Links
Entrez Gene 604
Application

Application

Western blot analysis of Bcl-6 Antibody (C-term) (Cat.# AP7372b) in mouse cerebellum tissue lysates (35ug/lane). BCL6 (arrow) was detected using the purified Pab.

Application

Formalin-fixed and paraffin-embedded human lymph tissue with Bcl-6 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Application

Bcl-6 Antibody (C-term) flow cytometry analysis of Jurkat cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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