Application
BCL10 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the BCL10 antibody detected the BCL10 protein (arrow).Application
BCL10 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the BCL10 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
Confocal immunofluorescent analysis of BCL10 Antibody (N-term) (Cat#AP10698a) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).Application
BCL10 Antibody (N-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | BCL10 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCIFFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CIPER, CLAP |
|---|---|
| Alternative Names | BCL10 CIPER CLAP B-cell lymphoma/leukemia 10 B-cell CLL/lymphoma 10 CARD-containing molecule enhancing NF-kappa-B CARD-like apoptotic protein CED-3/ICH-1 prodomain homologous E10-like regulator Cellular homolog of vCARMEN Cellular-E10 Mammalian C |
| Molecular Weight(MW) | 26252 Da |
| Function | Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1 |
| Tissue Specificity | Ubiquitous. |
| Cellular Localization | Cytoplasm, perinuclear region. Membrane raft. Note=Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts |
| Entrez Gene | 8915 |
|---|---|
| Nucleotide Accession | NP_003912.1 |
Application
BCL10 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the BCL10 antibody detected the BCL10 protein (arrow).
Application
BCL10 antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of the BCL10 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
Confocal immunofluorescent analysis of BCL10 Antibody (N-term) (Cat#AP10698a) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Application
BCL10 Antibody (N-term) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
