Western blot analysis of BCL11A Antibody (C-term) in Jurkat, Ramos, 293, NCI-H460 cell line lysates (35ug/lane). BCL11A (arrow) was detected using the purified Pab.
BCL11A CTIP1 EVI9 KIAA1809 ZNF856 B-cell lymphoma/leukemia 11A B-cell CLL/lymphoma 11A COUP-TF-interacting protein 1 Ecotropic viral integration site 9 protein homolog Zinc finger protein 856
Molecular Weight(MW)
91197 Da
Function
Functions as a myeloid and B-cell proto-oncogene. May play important roles in leukemogenesis and hematopoiesis. An essential factor in lymphopoiesis, is required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity)
Tissue Specificity
Expressed at high levels in brain, spleen thymus, bone marrow and testis. Expressed in CD34-positive myeloid precursor cells, B-cells, monocytes and megakaryocytes. Expression is tightly regulated during B-cell development
Cellular Localization
Cytoplasm. Nucleus. Note=Associates with the nuclear body. Colocalizes with SUMO1 and SENP2 in nuclear speckles (By similarity)
Western blot analysis of BCL11A Antibody (C-term) in Jurkat, Ramos, 293, NCI-H460 cell line lysates (35ug/lane). BCL11A (arrow) was detected using the purified Pab.
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.