Western blot analysis of extract from A431 cells, untreated ortreated with EGF (200ng/ml, 5min), using Bcr Antibody (Y177)(#AE1006a, Lane 1 and 2) and Phospho-Bcr-Y177 Antibody (#AE1006b,Lane 3 and 4).
Renal carcinoma antigen NY-REN-26; Breakpoint cluster region protein
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
WB:1:500~1:1000
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
BCR1 D22S11
Alternative Names
Renal carcinoma antigen NY-REN-26 Breakpoint cluster region protein
Molecular Weight(MW)
142819 Da
Function
GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity
Tissue Specificity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Western blot analysis of extract from A431 cells, untreated ortreated with EGF (200ng/ml, 5min), using Bcr Antibody (Y177)(#AE1006a, Lane 1 and 2) and Phospho-Bcr-Y177 Antibody (#AE1006b,Lane 3 and 4).
Application Notes
WB:1:500~1:1000
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.