Application
A. Western blot analysis on human brain lysate using anti-Beta-Dystroglycan RabMAb (Cat. #AJ1095a).| Product Name | Beta-Dystroglycan Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DAG1, Beta-dystroglycan, Dystrophin-associated glycoprotein 1 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EP2200Y |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | DAG1 Beta-dystroglycan Dystrophin-associated glycoprotein 1 |
|---|---|
| Molecular Weight(MW) | 97441 Da |
| Function | The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non-muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell adhesion-mediated signaling and implicated in cell polarity |
| Tissue Specificity | Expressed in a variety of fetal and adult tissues. In epidermal tissue, located to the basement membrane Also expressed in keratinocytes and fibroblasts |
| Cellular Localization | Alpha-dystroglycan: Secreted, extracellular space |
| Entrez Gene | 1605 |
|---|
Application
A. Western blot analysis on human brain lysate using anti-Beta-Dystroglycan RabMAb (Cat. #AJ1095a).| Application Notes | WB:1:1000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
