Application
BEX1 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the BEX1 antibody detected the BEX1 protein (arrow).Application
BEX1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BEX1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
BEX1 Antibody (Center) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | BEX1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BEX1; Protein BEX1; Brain-expressed X-linked protein 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | BEX1 Protein BEX1 Brain-expressed X-linked protein 1 |
|---|---|
| Molecular Weight(MW) | 14860 Da |
| Function | Signaling adapter molecule involved in p75NTR/NGFR signaling. Plays a role in cell cycle progression and neuronal differentiation. Inhibits neuronal differentiation in response to nerve growth factor (NGF). May act as a link between the cell cycle and neurotrophic factor signaling, possibly by functioning as an upstream modulator of receptor signaling, coordinating biological responses to external signals with internal cellular states (By similarity) |
| Tissue Specificity | Expressed in central nervous system, with high level in pituitary, cerebellum and temporal lobe. Expressed in lung, skeletal muscle, peripheral blood leukocyte, stomach, lymph node, trachea and bone marrow. Highly expressed in acute myeloid leukemia |
| Cellular Localization | Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus (By similarity) |
| Entrez Gene | 55859 |
|---|---|
| Nucleotide Accession | NP_060946.3 |
Application
BEX1 Antibody (Center) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the BEX1 antibody detected the BEX1 protein (arrow).
Application
BEX1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BEX1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
BEX1 Antibody (Center) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
