Application
BIN1 Antibody (Center) western blot analysis in L929 cell line lysates (35ug/lane).This demonstrates the BIN1 antibody detected the BIN1 protein (arrow).Application
BIN1 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the BIN1 antibody detected the BIN1 protein (arrow).Application
BIN1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BIN1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | BIN1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BIN1; AMPHL; Myc box-dependent-interacting protein 1; Amphiphysin II; Amphiphysin-like protein; Box-dependent myc-interacting protein 1; Bridging integrator 1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | AMPHL |
|---|---|
| Alternative Names | BIN1 AMPHL Myc box-dependent-interacting protein 1 Amphiphysin II Amphiphysin-like protein Box-dependent myc-interacting protein 1 Bridging integrator 1 |
| Molecular Weight(MW) | 64699 Da |
| Function | May be involved in regulation of synaptic vesicle endocytosis. May act as a tumor suppressor and inhibits malignant cell transformation |
| Tissue Specificity | Ubiquitous. Highest expression in the brain and muscle. Isoform IIA is expressed only in the brain where it is concentrated in axon initial segments and nodes of Ranvier Isoform BIN1 is widely expressed with highest expression in skeletal muscle |
| Cellular Localization | Isoform BIN1: Nucleus. |
| Entrez Gene | 274 |
|---|---|
| Nucleotide Accession | NP_647595.1 NP_647594.1 NP_004296.1 |
Application
BIN1 Antibody (Center) western blot analysis in L929 cell line lysates (35ug/lane).This demonstrates the BIN1 antibody detected the BIN1 protein (arrow).
Application
BIN1 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the BIN1 antibody detected the BIN1 protein (arrow).
Application
BIN1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BIN1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
