Application
The anti-Bik BH3 domain Pab is used in Western blot to detect Bik BH3 in mouse brain tissue lysate.Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.Application
Bik Antibody (BH3) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the Bik antibody detected the Bik protein (arrow).| Product Name | Bik BH3 Domain Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BIK; NBK; Bcl-2-interacting killer; Apoptosis inducer NBK; BIP1; BP4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NBK |
|---|---|
| Alternative Names | BIK NBK Bcl-2-interacting killer Apoptosis inducer NBK BIP1 BP4 |
| Molecular Weight(MW) | 18016 Da |
| Function | Accelerates programmed cell death. Association to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity Does not interact with BAX |
| Tissue Specificity | This Bik BH3 Domain antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50~80 amino acids selected from the N-terminal region (BH3 domain) of human Bik. |
| Cellular Localization | Endomembrane system; Single-pass membrane protein. Mitochondrion membrane; Single-pass membrane protein (By similarity). Note=Around the nuclear envelope, and in cytoplasmic membranes |
| Entrez Gene | 638 |
|---|
Application
The anti-Bik BH3 domain Pab is used in Western blot to detect Bik BH3 in mouse brain tissue lysate.
Application
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Application
Bik Antibody (BH3) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the Bik antibody detected the Bik protein (arrow).| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
