BLOC1S3 Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the BLOC1S3 antibody detected the BLOC1S3 protein (arrow).
BLOC1S3; BLOS3; Biogenesis of lysosome-related organelles complex 1 subunit 3
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
BLOS3
Alternative Names
BLOC1S3 BLOS3 Biogenesis of lysosome-related organelles complex 1 subunit 3
Molecular Weight(MW)
21256 Da
Function
Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking
Tissue Specificity
This BLOC1S3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-202 amino acids from the C-terminal region of human BLOC1S3.
BLOC1S3 Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the BLOC1S3 antibody detected the BLOC1S3 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.