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Bmp4 Antibody (N-term)

Catalog Number:OM227696
OM227696
Discount Price
OM227696-100ul
1~2 Week
100ul
OM227696-50ul
50ul
OM227696-20ul
20ul
1~2 Week
Product Profile
Product Name Bmp4 Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias BMP4; BMP2B; DVR4; Bone morphogenetic protein 4; Bone morphogenetic protein 2B
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms BMP2B
DVR4
Alternative Names BMP4
BMP2B
DVR4
Bone morphogenetic protein 4
Bone morphogenetic protein 2B
Molecular Weight(MW) 46555 Da
Function Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity)
Tissue Specificity Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines
Cellular Localization Secreted, extracellular space, extracellular matrix
Database Links
Entrez Gene 652
Nucleotide Accession NP_001193
Application

Application

Bmp4 Antibody (G20) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the Bmp4 antibody detected the Bmp4 protein (arrow).

Application

Western blot analysis of Bmp4 (arrow) using rabbit polyclonal Bmp4 Antibody (G20) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Bmp4 gene.

Application

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Bmp4 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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