Application
BMPR1B Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the BMPR1B antibody detected the BMPR1B protein (arrow).Application
BMPR1B Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BMPR1B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | BMPR1B Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BMPR1B; Bone morphogenetic protein receptor type-1B; CD_antigen=CDw293; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | BMPR1B Bone morphogenetic protein receptor type-1B CD_antigen=CDw293 Flags: Precursor |
|---|---|
| Molecular Weight(MW) | 56930 Da |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5 |
| Tissue Specificity | This BMPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-168 amino acids from the Central region of human BMPR1B. |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 658 |
|---|---|
| Nucleotide Accession | NP_001194.1 |
Application
BMPR1B Antibody (Center) western blot analysis in U251 cell line lysates (35ug/lane).This demonstrates the BMPR1B antibody detected the BMPR1B protein (arrow).
Application
BMPR1B Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BMPR1B Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
