Application
Western blot analysis of anti-BMPR1B Pab (Cat. #ap2005c) in NCI-H460 cell lysate. BMPR1B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.| Product Name | BMPR1B Antibody (N-term D17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BMPR1B; Bone morphogenetic protein receptor type-1B; CD_antigen=CDw293; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | BMPR1B Bone morphogenetic protein receptor type-1B CD_antigen=CDw293 Flags: Precursor |
|---|---|
| Molecular Weight(MW) | 56930 Da |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5 |
| Tissue Specificity | This BMPR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10~39 amino acids from the N-terminal region of human BMPR1B. |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
Application
Western blot analysis of anti-BMPR1B Pab (Cat. #ap2005c) in NCI-H460 cell lysate. BMPR1B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
