Application
BRUNOL5 Antibody (Center) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the BRUNOL5 Antibody detected the BRUNOL5 protein (arrow).| Product Name | BRUNOL5 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CELF5; BRUNOL5; CUGBP Elav-like family member 5; Bruno-like protein 5; CUG-BP- and ETR-3-like factor 5; RNA-binding protein BRUNOL-5 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BRUNOL5 |
|---|---|
| Alternative Names | CELF5 BRUNOL5 CUGBP Elav-like family member 5 Bruno-like protein 5 CUG-BP- and ETR-3-like factor 5 RNA-binding protein BRUNOL-5 |
| Molecular Weight(MW) | 52355 Da |
| Function | RNA-binding protein implicated in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA |
| Tissue Specificity | Expressed in brain. |
| Cellular Localization | Nucleus (By similarity). Cytoplasm (By similarity) |
| Entrez Gene | 60680 |
|---|---|
| Nucleotide Accession | NP_068757.2 |
Application
BRUNOL5 Antibody (Center) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the BRUNOL5 Antibody detected the BRUNOL5 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
