Application
BRUNOL6 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BRUNOL6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
BRUNOL6 Antibody (N-term) western blot analysis in mouse kidney,liver tissue lysates (35ug/lane).This demonstrates the BRUNOL6 antibody detected the BRUNOL6 protein (arrow).| Product Name | BRUNOL6 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CELF6; BRUNOL6; CUGBP Elav-like family member 6; Bruno-like protein 6; CUG-BP- and ETR-3-like factor 6; RNA-binding protein BRUNOL-6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHCWB |
| IHC:1:50~100 WB |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BRUNOL6 |
|---|---|
| Alternative Names | CELF6 BRUNOL6 CUGBP Elav-like family member 6 Bruno-like protein 6 CUG-BP- and ETR-3-like factor 6 RNA-binding protein BRUNOL-6 |
| Molecular Weight(MW) | 50477 Da |
| Function | RNA-binding protein implicated in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of TNNT2 in a muscle-specific splicing enhancer (MSE)-dependent manner. Promotes also exon exclusion of INSR pre-mRNA |
| Tissue Specificity | Expressed mainly in kidney, brain and testis and present in other tissues albeit at lower levels. Also expressed in fetal kidney |
| Cellular Localization | Nucleus (By similarity). Cytoplasm (By similarity) |
| Entrez Gene | 60677 |
|---|---|
| Nucleotide Accession | NP_001166155.1 NP_443072.3 |
Application
BRUNOL6 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BRUNOL6 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
BRUNOL6 Antibody (N-term) western blot analysis in mouse kidney,liver tissue lysates (35ug/lane).This demonstrates the BRUNOL6 antibody detected the BRUNOL6 protein (arrow).| Application Notes | IHC:1:50~100 WB |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
