Application
Western blot analysis of BSND Antibody (C-term) in mouse liver tissue lysates (35ug/lane). BSND (arrow) was detected using the purified Pab.Application
BSND Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded mouse kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BSND Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | BSND Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | BSND; BART; Barttin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BART |
|---|---|
| Alternative Names | BSND BART Barttin |
| Molecular Weight(MW) | 35197 Da |
| Function | Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter |
| Tissue Specificity | Expressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear |
| Cellular Localization | Cell membrane; Multi-pass membrane protein (By similarity). Cytoplasm (By similarity). Note=A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral (By similarity) |
| Entrez Gene | 7809 |
|---|
Application
Western blot analysis of BSND Antibody (C-term) in mouse liver tissue lysates (35ug/lane). BSND (arrow) was detected using the purified Pab.
Application
BSND Antibody (C-term) IHC analysis in formalin fixed and paraffin embedded mouse kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the BSND Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
