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C10orf90 Antibody (C-term)

Catalog Number:OM227927
OM227927
Discount Price
OM227927-100ul
1~2 Week
100ul
OM227927-50ul
50ul
OM227927-20ul
20ul
1~2 Week
Product Profile
Product Name C10orf90 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias C10orf90; FATS; Centrosomal protein C10orf90; Fragile-site associated tumor suppressor homolog
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms FATS
Alternative Names C10orf90
FATS
Centrosomal protein C10orf90
Fragile-site associated tumor suppressor homolog
Molecular Weight(MW) 77910 Da
Function Tumor suppressor that is required to sustain G2/M checkpoint after DNA damage. Mediates CDKN1A/p21 protein stability in a ubiquitin-independent manner (By similarity). May have a role in the assembly of primary cilia
Tissue Specificity This C10orf90 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 593-623 amino acids from the C-terminal region of human C10orf90.
Cellular Localization Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Note=Localizes to the actin cytoskeleton in a proportion of cells. Colocalizes with centriolar acetylated tubulin
Database Links
Entrez Gene 118611
Application

Application

Western blot analysis of C10orf90 Antibody (C-term) in A2058 cell line lysates (35ug/lane).C10orf90 (arrow) was detected using the purified Pab.

Application

C10orf90 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the C10orf90 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

C10orf90 Antibody (C-term) flow cytometric analysis of A2058 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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