Application
C17orf71 Antibody (N-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the C17orf71 antibody detected C17orf71 protein (arrow).| Product Name | C17orf71 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | SMG8; ABC2; C17orf71; Protein SMG8; Amplified in breast cancer gene 2 protein; Protein smg-8 homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ABC2 C17orf71 |
|---|---|
| Alternative Names | SMG8 ABC2 C17orf71 Protein SMG8 Amplified in breast cancer gene 2 protein Protein smg-8 homolog |
| Molecular Weight(MW) | 109684 Da |
| Function | Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited by release factors to stalled ribosomes together with SMG1 and SMG9 (forming the SMG1C protein kinase complex) and, in the SMG1C complex, is required to mediate the recruitment of SMG1 to the ribosome:SURF complex and to suppress SMG1 kinase activity until the ribosome:SURF complex locates the exon junction complex (EJC) Acts as a regulator of kinase activity |
| Tissue Specificity | This C17orf71 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the N-terminal region of human C17orf71. |
| Entrez Gene | 55181 |
|---|---|
| Nucleotide Accession | NP_060619.4 |
Application
C17orf71 Antibody (N-term) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the C17orf71 antibody detected C17orf71 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
