Application
Western blot analysis of C19orf46 Antibody (Center) in K562 cell line lysates (35ug/lane). C19orf46 (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with ZYG11B Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
C19orf46 Antibody (Center) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | C19orf46 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C19orf46; Nesprin-4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C19orf46 |
|---|---|
| Alternative Names | C19orf46 Nesprin-4 |
| Molecular Weight(MW) | 43512 Da |
| Function | Contributes to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity) |
| Tissue Specificity | This C19orf46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201~231 amino acids from the Central region of human C19orf46. |
| Cellular Localization | Nucleus outer membrane; Single-pass type IV membrane protein (By similarity). Note=The nucleus outer membrane location requires the presence of a SUN domain-containing protein (By similarity) |
| Entrez Gene | 163183 |
|---|
Application
Western blot analysis of C19orf46 Antibody (Center) in K562 cell line lysates (35ug/lane). C19orf46 (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with ZYG11B Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
C19orf46 Antibody (Center) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
