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C1orf88 Antibody (C-term)

Catalog Number:OM228179
OM228179
Discount Price
OM228179-100ul
1~2 Week
100ul
OM228179-50ul
50ul
OM228179-20ul
20ul
1~2 Week
Product Profile
Product Name C1orf88 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias PIFO; C1orf88; Protein pitchfork
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms C1orf88
Alternative Names PIFO
C1orf88
Protein pitchfork
Molecular Weight(MW) 21973 Da
Function During primary cilia disassembly, involved in cilia disassembly. Required specifically to control cilia retraction as well as the liberation and duplication of the basal body/centrosome. May act by stimulating AURKA activity at the basal body in a cell cycle-dependent manner
Tissue Specificity This C1orf88 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-190 amino acids from the C-terminal region of human C1orf88.
Cellular Localization Cytoplasmic vesicle (By similarity). Golgi apparatus, trans-Golgi network (By similarity). Cytoplasm (By similarity). Note=Accumulates specifically at the basal body and ciliary necklace during the early steps of cilia assembly and disassembly, when structural, functional and regulatory proteins are delivered to cilia (By similarity). At S phase, accumulates in vesicles and declines during mitosis (By similarity)
Database Links
Entrez Gene 128344
Nucleotide Accession NP_857594.2
Application

Application

C1orf88 Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the C1orf88 antibody detected C1orf88 protein (arrow).

Application

C1orf88 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the C1orf88 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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