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C2orf60 Antibody (Center)

Catalog Number:OM228265
OM228265
Discount Price
OM228265-100ul
1~2 Week
100ul
OM228265-50ul
50ul
OM228265-20ul
20ul
1~2 Week
Product Profile
Product Name C2orf60 Antibody (Center)
Antibody Type Primary Antibodies
Antigen Alias TYW5; C2orf60; tRNA wybutosine-synthesizing protein 5
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBFC
WB:1:100~500 FC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms C2orf60
Alternative Names TYW5
C2orf60
tRNA wybutosine-synthesizing protein 5
Molecular Weight(MW) 36548 Da
Function tRNA hydroxylase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the hydroxylation of 7-(a-amino-a-carboxypropyl)wyosine (yW-72) into undermodified hydroxywybutosine (OHyW*). OHyW* being further transformed into hydroxywybutosine (OHyW) by LCMT2/TYW4. OHyW is a derivative of wybutosine found in higher eukaryotes
Tissue Specificity This C2orf60 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-132 amino acids from the Central region of human C2orf60.
Database Links
Entrez Gene 129450
Nucleotide Accession NP_001034782.1
Application

Application

C2orf60 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the C2orf60 antibody detected the C2orf60 protein (arrow).

Application

C2orf60 Antibody (Center) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the C2orf60 antibody detected the C2orf60 protein (arrow).

Application

C2orf60 Antibody (Center) flow cytometric analysis of A375 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 FC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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