Application
C4BPA Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the C4BPA antibody detected the C4BPA protein (arrow).Application
C4BPA antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the C4BPA antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.Application
C4BPA Antibody (C-term) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | C4BPA Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C4BPA; C4BP; C4b-binding protein alpha chain; Proline-rich protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C4BP |
|---|---|
| Alternative Names | C4BPA C4BP C4b-binding protein alpha chain Proline-rich protein |
| Molecular Weight(MW) | 67033 Da |
| Function | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. Alpha chain binds C4b. It interacts also with anticoagulant protein S and with serum amyloid P component |
| Tissue Specificity | Chylomicrons in the plasma. |
| Cellular Localization | Secreted. |
| Entrez Gene | 722 |
|---|---|
| Nucleotide Accession | NP_000706.1 |
Application
C4BPA Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the C4BPA antibody detected the C4BPA protein (arrow).
Application
C4BPA antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the C4BPA antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
C4BPA Antibody (C-term) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
