Application
C4BPB Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the C4BPB antibody detected the C4BPB protein (arrow).Application
Western blot analysis of C4BPB (arrow) using rabbit polyclonal C4BPB Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the C4BPB gene.| Product Name | C4BPB Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | C4BPB; C4b-binding protein beta chain |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | C4BPB C4b-binding protein beta chain |
|---|---|
| Molecular Weight(MW) | 28357 Da |
| Function | Controls the classical pathway of complement activation. It binds as a cofactor to C3b/C4b inactivator (C3bINA), which then hydrolyzes the complement fragment C4b. It also accelerates the degradation of the C4bC2a complex (C3 convertase) by dissociating the complement fragment C2a. It also interacts with anticoagulant protein S and with serum amyloid P component. The beta chain binds protein S |
| Tissue Specificity | This C4BPB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-153 amino acids from the Central region of human C4BPB. |
| Cellular Localization | Secreted. |
| Entrez Gene | 725 |
|---|---|
| Nucleotide Accession | NP_001017365.1 NP_001017367.1 NP_000707.1 |
Application
C4BPB Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the C4BPB antibody detected the C4BPB protein (arrow).
Application
Western blot analysis of C4BPB (arrow) using rabbit polyclonal C4BPB Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the C4BPB gene.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
