Application
C4orf49 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the C4orf49 antibody detected the C4orf49 protein (arrow).Application
C4orf49 Antibody (C-term) (AP14729b)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of C4orf49 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | C4orf49 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MGARP; C4orf49; CESP1; HUMMR; OSAP; Protein MGARP; Corneal endothelium-specific protein 1; Hypoxia up-regulated mitochondrial movement regulator protein; Mitochondria-localized glutamic acid-rich protein; Ovary-specific acidic protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C4orf49 CESP1 HUMMR OSAP |
|---|---|
| Alternative Names | MGARP C4orf49 CESP1 HUMMR OSAP Protein MGARP Corneal endothelium-specific protein 1 Hypoxia up-regulated mitochondrial movement regulator protein Mitochondria-localized glutamic acid-rich protein Ovary-specific acidic protein |
| Molecular Weight(MW) | 25390 Da |
| Function | Plays a role in the trafficking of mitochondria along microtubules. Regulates the kinesin-mediated axonal transport of mitochondria to nerve terminals along microtubules during hypoxia Participates in the translocation of TRAK2/GRIF1 from the cytoplasm to the mitochondrion. Also plays a role in steroidogenesis through maintenance of mitochondrial abundance and morphology (By similarity) |
| Tissue Specificity | Expressed in the brain, adrenal gland and corneal endothelium (CE). Expressed in steroid-producing cells of the ovary and testis (at protein level). Expressed in steroid- producing cells of the ovary and testis. Weakly expressed in placenta. Expressed in corneal endothelial cells |
| Cellular Localization | Membrane; Single-pass membrane protein (Potential). Mitochondrion. Mitochondrion outer membrane; Single- pass type IV membrane protein; Cytoplasmic side (By similarity) Note=Colocalizes with RHOT1, RHOT2, TRAK1 and TRAK2 at the mitochondrion (By similarity) |
| Entrez Gene | 84709 |
|---|---|
| Nucleotide Accession | NP_116012.2 |
Application
C4orf49 Antibody (C-term) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the C4orf49 antibody detected the C4orf49 protein (arrow).
Application
C4orf49 Antibody (C-term) (AP14729b)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of C4orf49 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
