C6orf167 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the C6orf167 antibody detected the C6orf167 protein (arrow).
MMS22L; C6orf167; Protein MMS22-like; Methyl methanesulfonate-sensitivity protein 22-like
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
C6orf167
Alternative Names
MMS22L C6orf167 Protein MMS22-like Methyl methanesulfonate-sensitivity protein 22-like
Molecular Weight(MW)
142321 Da
Function
Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork- associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA
Tissue Specificity
This C6orf167 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-81 amino acids from the N-terminal region of human C6orf167.
Cellular Localization
Nucleus. Note=Localizes to DNA damage sites, accumulates at stressed replication forks
C6orf167 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the C6orf167 antibody detected the C6orf167 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.