Application
western blot Western blot analysis of C8orf41 Antibody (N-term) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in CEM cell line lysate. C8orf41 Antibody (N-term) (arrow) was detected using the purified Pab (1:60/250 dilution).| Product Name | C8orf41 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | TTI2; C8orf41; TELO2-interacting protein 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C8orf41 |
|---|---|
| Alternative Names | TTI2 C8orf41 TELO2-interacting protein 2 |
| Molecular Weight(MW) | 56915 Da |
| Function | Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs |
| Tissue Specificity | This C8orf41 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-77 amino acids from the N-terminal region of human C8orf41. |
| Entrez Gene | 80185 |
|---|---|
| Nucleotide Accession | NP_079391.2 |
Application
western blot Western blot analysis of C8orf41 Antibody (N-term) Pab pre-incubated without(lane 1) and with(lane 2) blocking peptide in CEM cell line lysate. C8orf41 Antibody (N-term) (arrow) was detected using the purified Pab (1:60/250 dilution).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
