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C9orf126 Antibody (C-term)

Catalog Number:OM228409
OM228409
Discount Price
OM228409-100ul
1~2 Week
100ul
OM228409-50ul
50ul
OM228409-20ul
20ul
1~2 Week
Product Profile
Product Name C9orf126 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias SCAI; C9orf126; Protein SCAI; Suppressor of cancer cell invasion protein
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms C9orf126
Alternative Names SCAI
C9orf126
Protein SCAI
Suppressor of cancer cell invasion protein
Molecular Weight(MW) 70399 Da
Function Tumor suppressor which functions to suppress MKL1- induced SRF transcriptional activity. May function in the RHOA- DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1
Tissue Specificity This C9orf126 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 553-582 amino acids from the C-terminal region of human C9orf126.
Cellular Localization Membrane; Single-pass membrane protein (Potential). Nucleus. Cytoplasm. Note=Nuclear localization is required for inhibition of MKL1 (By similarity)
Database Links
Entrez Gene 286205
Nucleotide Accession NP_001138349.1 NP_775961.2
Application

Application

C9orf126 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the C9orf126 antibody detected the C9orf126 protein (arrow).

Application

C9orf126 Antibody (C-term) western blot analysis in CHO cell line lysates (35ug/lane).This demonstrates the C9orf126 antibody detected the C9orf126 protein (arrow).

Application

C9orf126 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the C9orf126 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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