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CACNA2D3 Antibody (C-term)

Catalog Number:OM228509
OM228509
Discount Price
OM228509-100ul
1~2 Week
100ul
OM228509-50ul
50ul
OM228509-20ul
20ul
1~2 Week
Product Profile
Product Name CACNA2D3 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias CACNA2D3; Voltage-dependent calcium channel subunit alpha-2/delta-3; Voltage-gated calcium channel subunit alpha-2/delta-3; Voltage-dependent calcium channel subunit alpha-2-3; Voltage-dependent calcium channel subunit delta-3
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBFC
WB:1:100~500 FC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names CACNA2D3
Voltage-dependent calcium channel subunit alpha-2/delta-3
Voltage-gated calcium channel subunit alpha-2/delta-3
Voltage-dependent calcium channel subunit alpha-2-3
Voltage-dependent calcium channel subunit delta-3
Molecular Weight(MW) 123011 Da
Function The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Acts as a regulatory subunit for P/Q-type calcium channel (CACNA1A), N-type (CACNA1B), L-type (CACNA1C OR CACNA1D) but not T-type (CACNA1G) (By similarity)
Tissue Specificity Only detected in brain. Not present in lung, testis, aorta, spleen, jejunum, ventricular muscle and kidney (at protein level). According to PubMed:11687876, it is brain- specific, while according to PubMed:11245980, it is widely expressed
Cellular Localization Membrane; Single-pass type I membrane protein (Potential)
Database Links
Entrez Gene 55799
Application

Application

Western blot analysis of CACNA2D3 Antibody (C-term) in HepG2 cell line lysates (35ug/lane). CACNA2D3 (arrow) was detected using the purified Pab.

Application

CACNA2D3 Antibody (C-term) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 FC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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