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CACNG5 Antibody (C-term)

Catalog Number:OM228524
OM228524
Discount Price
OM228524-100ul
1~2 Week
100ul
OM228524-50ul
50ul
OM228524-20ul
20ul
1~2 Week
Product Profile
Product Name CACNG5 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias CACNG5; Voltage-dependent calcium channel gamma-5 subunit; Neuronal voltage-gated calcium channel gamma-5 subunit; Transmembrane AMPAR regulatory protein gamma-5
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names CACNG5
Voltage-dependent calcium channel gamma-5 subunit
Neuronal voltage-gated calcium channel gamma-5 subunit
Transmembrane AMPAR regulatory protein gamma-5
Molecular Weight(MW) 30903 Da
Function Regulates the gating properties of AMPA-selective glutamate receptors (AMPARs). Modulates their gating properties by accelerating their rates of activation, deactivation and desensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity for GRIA1, GRIA4 and the long isoform of GRIA2. Thought to stabilize the calcium channel in an inactivated (closed) state (By similarity)
Tissue Specificity This CACNG5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 199~228 amino acids from the C-terminal region of human CACNG5.
Cellular Localization Membrane; Multi-pass membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity)
Database Links
Entrez Gene 27091
Application

Application

Western blot analysis of CACNG5 antibody (C-term) in K562 cell line lysates (35ug/lane). CACNG5 (arrow) was detected using the purified Pab.

Application

Formalin-fixed and paraffin-embedded human brain tissue reacted with CACNG5 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Application

Flow cytometric analysis of K562 cells using CACNG5 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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