Application
Western blot analysis on (A) HeLa (B) A431 (C) SH-SY5Y and (D) HepG2 cell lysates using anti-Calnexin RabMAb (Cat. #AJ1119a).Application
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Calnexin RabMAb (Cat. #AJ1119a).| Product Name | Calnexin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CANX, Calnexin, Major histocompatibility complex class I antigen-binding protein p88;p90;IP90 |
| Clonality | Monoclonal |
|---|---|
| Clone Number | EPR3632 |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:20000~100000 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CANX Calnexin Major histocompatibility complex class I antigen-binding protein p88 p90 IP90 |
|---|---|
| Molecular Weight(MW) | 67568 Da |
| Function | Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor- mediated endocytosis at the synapse |
| Tissue Specificity | A synthetic peptide corresponding to residues in human Calnexin was used as an immunogen. |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. The palmitoylated form preferentially localizes to the perinuclear rough ER |
| Entrez Gene | 821 |
|---|
Application
Western blot analysis on (A) HeLa (B) A431 (C) SH-SY5Y and (D) HepG2 cell lysates using anti-Calnexin RabMAb (Cat. #AJ1119a).
Application
Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Calnexin RabMAb (Cat. #AJ1119a).| Application Notes | WB:1:20000~100000 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
