Application
CAPN6 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CAPN6 antibody detected the CAPN6 protein (arrow).Application
CAPN6 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CAPN6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CAPN6 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CAPN6; CALPM; CANPX; Calpain-6; Calpain-like protease X-linked; Calpamodulin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CALPM CANPX |
|---|---|
| Alternative Names | CAPN6 CALPM CANPX Calpain-6 Calpain-like protease X-linked Calpamodulin |
| Molecular Weight(MW) | 74576 Da |
| Function | Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues (By similarity) |
| Tissue Specificity | Expressed only in placenta. |
| Cellular Localization | Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, spindle. Note=During mitose associated with the mitotic spindle. At telophase colocalized to the midbody spindle |
| Entrez Gene | 827 |
|---|---|
| Nucleotide Accession | NP_055104.2 |
Application
CAPN6 Antibody (Center) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the CAPN6 antibody detected the CAPN6 protein (arrow).
Application
CAPN6 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CAPN6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
