Application
CAPN8 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the CAPN8 antibody detected the CAPN8 protein (arrow).Application
CAPN8 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CAPN8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CAPN8 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CAPN8; NCL2; Calpain-8; New calpain 2; Stomach-specific M-type calpain |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NCL2 |
|---|---|
| Alternative Names | CAPN8 NCL2 Calpain-8 New calpain 2 Stomach-specific M-type calpain |
| Molecular Weight(MW) | 79144 Da |
| Function | Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex (By similarity) |
| Tissue Specificity | Stomach. |
| Cellular Localization | Cytoplasm (By similarity). Golgi apparatus (By similarity) |
| Entrez Gene | 388743 |
|---|---|
| Nucleotide Accession | NP_001137434.1 |
Application
CAPN8 Antibody (Center) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the CAPN8 antibody detected the CAPN8 protein (arrow).
Application
CAPN8 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CAPN8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
