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CASK Antibody (Center K227)

Catalog Number:OM228715
OM228715
Discount Price
OM228715-100ul
1~2 Week
100ul
OM228715-50ul
50ul
OM228715-20ul
20ul
1~2 Week
Product Profile
Product Name CASK Antibody (Center K227)
Antibody Type Primary Antibodies
Antigen Alias CASK; LIN2; Peripheral plasma membrane protein CASK; Calcium/calmodulin-dependent serine protein kinase; Protein lin-2 homolog
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:50~100
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms LIN2
Alternative Names CASK
LIN2
Peripheral plasma membrane protein CASK
Calcium/calmodulin-dependent serine protein kinase
Protein lin-2 homolog
Molecular Weight(MW) 105123 Da
Function Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking Contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1 Binds to cell-surface proteins, including amyloid precursor protein, neurexins and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1
Tissue Specificity Ubiquitous. Expression is significantly greater in brain relative to kidney, lung, and liver and in fetal brain and kidney relative to lung and liver
Cellular Localization Nucleus (By similarity). Cytoplasm (By similarity). Cell membrane; Peripheral membrane protein (By similarity)
Database Links
Entrez Gene 8573
Application

Application

Western blot analysis of CASK (Center K227) in Hela cell line lysates (35ug/lane).CASK (arrow) was detected using the purified Pab.

Application

Western blot analysis of CASK (Center K227) in HL-60 cell line lysates (35ug/lane).CASK (arrow) was detected using the purified Pab.
Application Notes WB:1:50~100
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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