Application
Western blot analysis of CASP10 antibody (Center) in HepG2 cell line lysates (35ug/lane). CASP10 (arrow) was detected using the purified Pab.| Product Name | CASP10 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CASP10; MCH4; Caspase-10; Apoptotic protease Mch-4; FAS-associated death domain protein interleukin-1B-converting enzyme 2; ICE-like apoptotic protease 4; Caspase-10 subunit p23/17; Caspase-10 subunit p12 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MCH4 |
|---|---|
| Alternative Names | CASP10 MCH4 Caspase-10 Apoptotic protease Mch-4 FAS-associated death domain protein interleukin-1B-converting enzyme 2 ICE-like apoptotic protease 4 Caspase-10 subunit p23/17 Caspase-10 subunit p12 |
| Molecular Weight(MW) | 58951 Da |
| Function | Involved in the activation cascade of caspases responsible for apoptosis execution. Recruited to both Fas- and TNFR-1 receptors in a FADD dependent manner. May participate in the granzyme B apoptotic pathways. Cleaves and activates caspase- 3, -4, -6, -7, -8, and -9. Hydrolyzes the small- molecule substrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC |
| Tissue Specificity | Detectable in most tissues. Lowest expression is seen in brain, kidney, prostate, testis and colon |
| Entrez Gene | 843 |
|---|
Application
Western blot analysis of CASP10 antibody (Center) in HepG2 cell line lysates (35ug/lane). CASP10 (arrow) was detected using the purified Pab.| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
