Application
Western blot analysis of CASP14 Antibody (C-term) in A375 cell line lysates (35ug/lane). CASP14 (arrow) was detected using the purified Pab.(2ug/ml)| Product Name | CASP14 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CASP14; Caspase-14; Caspase-14 subunit p19; Caspase-14 subunit p10 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CASP14 Caspase-14 Caspase-14 subunit p19 Caspase-14 subunit p10 |
|---|---|
| Molecular Weight(MW) | 27680 Da |
| Function | Believed to be a non-apoptotic caspase which is involved in epidermal differentiation. Seems to play a role in keratinocyte differentiation and cornification. Probably regulates maturation of the epidermis by proteolytically processing filaggrin (By similarity) |
| Tissue Specificity | Expressed in keratinocytes of adult skin suprabasal layers (from spinous layers to the stratum granulosum and stratum corneum) (at protein level). Expressed in keratinocytes of hair shaft and sebaceous glands (at protein level). In psoriatic skin only expressed at very low levels |
| Cellular Localization | Cytoplasm. Nucleus. |
| Entrez Gene | 23581 |
|---|
Application
Western blot analysis of CASP14 Antibody (C-term) in A375 cell line lysates (35ug/lane). CASP14 (arrow) was detected using the purified Pab.(2ug/ml)| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
