Application
Western blot analysis of CATB Antibody (Center) (Cat.# AP7367c) in Y79 cell line lysates (35ug/lane). CATB (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma with CATB Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.Application
Flow cytometric analysis of HepG2 cells using CATB Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | CATB Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CTSB; CPSB; Cathepsin B; APP secretase; Cathepsin B1; Cathepsin B light chain; Cathepsin B heavy chain |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CPSB |
|---|---|
| Alternative Names | CTSB CPSB Cathepsin B APP secretase Cathepsin B1 Cathepsin B light chain Cathepsin B heavy chain |
| Molecular Weight(MW) | 37822 Da |
| Function | Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis |
| Tissue Specificity | This CATB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205~235 amino acids from the Center region of human CATB. |
| Cellular Localization | Lysosome. Melanosome. Secreted, extracellular space (By similarity). Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV |
| Entrez Gene | 1508 |
|---|
Application
Western blot analysis of CATB Antibody (Center) (Cat.# AP7367c) in Y79 cell line lysates (35ug/lane). CATB (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma with CATB Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application
Flow cytometric analysis of HepG2 cells using CATB Antibody (Center)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
