Application
CBX1 Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the CBX1 antibody detected the CBX1 protein (arrow).Application
CBX1 Antibody (C-term) (AP13741b)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CBX1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CBX1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CBX1; CBX; Chromobox protein homolog 1; HP1Hsbeta; Heterochromatin protein 1 homolog beta; Heterochromatin protein p25; M31; Modifier 1 protein; p25beta |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CBX |
|---|---|
| Alternative Names | CBX1 CBX Chromobox protein homolog 1 HP1Hsbeta Heterochromatin protein 1 homolog beta Heterochromatin protein p25 M31 Modifier 1 protein p25beta |
| Molecular Weight(MW) | 21418 Da |
| Function | Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane |
| Tissue Specificity | Expressed in all adult and embryonic tissues. |
| Cellular Localization | Nucleus. Note=Unassociated with chromosomes during mitosis |
| Entrez Gene | 10951 |
|---|---|
| Nucleotide Accession | NP_006798.1 NP_001120700.1 |
Application
CBX1 Antibody (C-term) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the CBX1 antibody detected the CBX1 protein (arrow).
Application
CBX1 Antibody (C-term) (AP13741b)immunohistochemistry analysis in formalin fixed and paraffin embedded human cerebellum tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CBX1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
