Application
Western blot analysis of CBX2 Antibody (N-term) in MDA-MB231 cell line lysates (35ug/lane). CBX2 (arrow) was detected using the purified Pab.| Product Name | CBX2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | CBX2; Chromobox protein homolog 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CBX2 Chromobox protein homolog 2 |
|---|---|
| Molecular Weight(MW) | 56081 Da |
| Function | Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Involved in sexual development, acting as activator of NR5A1 expression |
| Tissue Specificity | This CBX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CBX2. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 84733 |
|---|
Application
Western blot analysis of CBX2 Antibody (N-term) in MDA-MB231 cell line lysates (35ug/lane). CBX2 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
