Application
CBX3 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CBX3 antibody detected the CBX3 protein (arrow).| Product Name | CBX3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CBX3 Chromobox protein homolog 3 HECH Heterochromatin protein 1 homolog gamma Modifier 2 protein |
|---|---|
| Molecular Weight(MW) | 20811 Da |
| Function | Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins |
| Tissue Specificity | This CBX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the Central region of human CBX3. |
| Cellular Localization | Nucleus (Potential). Note=Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential) |
| Entrez Gene | 11335 |
|---|---|
| Nucleotide Accession | NP_009207.2 NP_057671.2 |
Application
CBX3 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the CBX3 antibody detected the CBX3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
