Application
CCL4 Antibody (Center) western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the CCL4 antibody detected CCL4 protein (arrow).Application
CCL4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CCL4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | CCL4 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | LAG1, MIP1B, SCYA4 |
|---|---|
| Alternative Names | CCL4 LAG1 MIP1B SCYA4 C-C motif chemokine 4 G-26 T-lymphocyte-secreted protein HC21 Lymphocyte activation gene 1 protein MIP-1-beta(1-69) Macrophage inflammatory protein 1-beta PAT 744 Protein H400 SIS-gamma Small-inducible cytokine A4 T-cell |
| Molecular Weight(MW) | 10212 Da |
| Function | Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B |
| Tissue Specificity | This CCL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-56 amino acids from the Central region of human CCL4. |
| Cellular Localization | Secreted. |
| Entrez Gene | 9560 |
|---|---|
| Nucleotide Accession | NP_996890.1 NP_002975.1 NP_001001435.1 |
Application
CCL4 Antibody (Center) western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the CCL4 antibody detected CCL4 protein (arrow).
Application
CCL4 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human prostate carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CCL4 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
