Application
CCL22 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CCL22 antibody detected the CCL22 protein (arrow).| Product Name | CCL22 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MDC, SCYA22 |
|---|---|
| Alternative Names | CCL22 MDC SCYA22 C-C motif chemokine 22 CC chemokine STCP-1 MDC(1-69) Macrophage-derived chemokine Small-inducible cytokine A22 Stimulated T-cell chemotactic protein 1 MDC(3-69) MDC(5-69) MDC(7-69) |
| Molecular Weight(MW) | 10625 Da |
| Function | May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes Binds to CCR4. Processed forms MDC(3-69), MDC(5-69) and MDC(7-69) seem not be active |
| Tissue Specificity | Highly expressed in macrophage and in monocyte-derived dendritic cells, and thymus. Also found in lymph node, appendix, activated monocytes, resting and activated macrophages. Lower expression in lung and spleen. Very weak expression in small intestine. In lymph node expressed in a mature subset of Langerhans' cells (CD1a+ and CD83+). Expressed in Langerhans' cell histiocytosis but not in dermatopathic lymphadenopathy. Expressed in atopic dermatitis, allergic contact dermatitis skin, and psoriasis, in both the epidermis and dermis |
| Cellular Localization | Secreted. |
| Entrez Gene | 6367 |
|---|---|
| Nucleotide Accession | NP_002981.2 |
Application
CCL22 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CCL22 antibody detected the CCL22 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
