Application
CCNDBP1 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CCNDBP1 antibody detected the CCNDBP1 protein (arrow).| Product Name | CCNDBP1 (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | DIP1, GCIP, HHM |
|---|---|
| Alternative Names | CCNDBP1 DIP1 GCIP HHM Cyclin-D1-binding protein 1 Grap2 and cyclin-D-interacting protein Human homolog of Maid |
| Molecular Weight(MW) | 40262 Da |
| Function | May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F- dependent transcription |
| Tissue Specificity | Ubiquitously expressed. Expression is down- regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas |
| Cellular Localization | Cytoplasm. Nucleus. |
| Entrez Gene | 23582 |
|---|---|
| Nucleotide Accession | NP_036274.3 |
Application
CCNDBP1 Antibody (N-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CCNDBP1 antibody detected the CCNDBP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
