Application
A. Immunohistochemical analysis of paraffin-embedded human spleen using anti-CCR2 RabMAb (Cat. #AJ1143a).Application
B. Flow cytometric analysis of permeabilized Jurkat cells using anti-CKR2 RabMAb (red) (Cat. #AJ1143a) or a rabbit IgG (negative) (green).Application
C. Western blot analysis of immunoprecipitation pellets using (1) Jurkat cell lysate or (2) 1X PBS (negative control), in the presence of anti-CCR2 RabMAb (Cat. #AJ1143a).| Product Name | CCR2/CKR2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Monoclonal |
|---|---|
| Clone Number | E68 |
| Host Species | Rabbit |
| Tested Applications | IHCFCWB |
| IHC:1:100 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | CMKBR2 |
|---|---|
| Alternative Names | CCR2 CMKBR2 C-C chemokine receptor type 2 Monocyte chemoattractant protein 1 receptor |
| Molecular Weight(MW) | 41915 Da |
| Function | Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection |
| Tissue Specificity | A synthetic peptide corresponding to the N-terminal residues of the human C-C chemokine receptor type 2 was used as immunogen. The antibody does not cross-react with other CKR family members. |
| Cellular Localization | Cell membrane; Multi-pass membrane protein. |
| Entrez Gene | 729230 |
|---|
Application
A. Immunohistochemical analysis of paraffin-embedded human spleen using anti-CCR2 RabMAb (Cat. #AJ1143a).
Application
B. Flow cytometric analysis of permeabilized Jurkat cells using anti-CKR2 RabMAb (red) (Cat. #AJ1143a) or a rabbit IgG (negative) (green).
Application
C. Western blot analysis of immunoprecipitation pellets using (1) Jurkat cell lysate or (2) 1X PBS (negative control), in the presence of anti-CCR2 RabMAb (Cat. #AJ1143a).| Application Notes | IHC:1:100 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
