Application
CCNT1 Antibody (Center) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the CCNT1 antibody detected the CCNT1 protein (arrow).Application
CCNT1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CCNT1 antibody detected the CCNT1 protein (arrow).Application
CCNT1 Antibody (Center) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | CCNT1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | CCNT1 Cyclin-T1 |
|---|---|
| Molecular Weight(MW) | 80685 Da |
| Function | Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which is proposed to facilitate the transition from abortive to productive elongation by phosphorylating the CTD (carboxy-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). In case of HIV or SIV infections, binds to the transactivation domain of the viral nuclear transcriptional activator, Tat, thereby increasing Tat's affinity for the transactivating response RNA element (TAR RNA) Serves as an essential cofactor for Tat, by promoting RNA Pol II activation, allowing transcription of viral genes |
| Tissue Specificity | Ubiquitously expressed. |
| Cellular Localization | Nucleus. |
Application
CCNT1 Antibody (Center) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the CCNT1 antibody detected the CCNT1 protein (arrow).
Application
CCNT1 Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CCNT1 antibody detected the CCNT1 protein (arrow).
Application
CCNT1 Antibody (Center) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
