Application
CCNY Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the CCNY antibody detected the CCNY protein (arrow).| Product Name | CCNY Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | C10orf9, CBCP1, CFP1 |
|---|---|
| Alternative Names | CCNY C10orf9 CBCP1 CFP1 Cyclin-Y Cyclin box protein 1 Cyclin fold protein 1 cyclin-X |
| Molecular Weight(MW) | 39337 Da |
| Function | Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Cell membrane; Lipid-anchor; Cytoplasmic side |
| Entrez Gene | 219771 |
|---|---|
| Nucleotide Accession | NP_659449.3 NP_859049.2 |
Application
CCNY Antibody (Center) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the CCNY antibody detected the CCNY protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
